A dominating blocker and outstanding athlete, Spencer and teammate George Mrkonic were recognized as two of college football's premier linemen during the early 1950s. Spencer excelled at right offensive tackle, helping the Jayhawks to a combined 15-5 mark during his two seasons as a regular on the offensive front. As a sophomore, Spencer was a backup at KU behind future pro football hall of famer Mike McCormack. Following his senior season, Spencer was selected to play in both the East-West Shrine Game and Senior Bowl. He played in the National Football League for the Detroit Lions and Green Bay Packers from 1953-61, and served as an offensive line coach for the Oakland Raiders for 19 seasons (1962-79).